Amyloid precursor proteins (APPs) are evolutionarily conserved membrane glycoproteins that undergo complex proteolytic processing to yield fragments with diverse biological activities. Beyond their ...

Share on Pinterest New research looks into the role of amyloid-beta in developing Alzheimer’s. Westend61/Getty Images A main theory behind the cause of Alzheimer’s disease is the build-up of the ...

(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...

Cerebral amyloid angiopathy is a major cause of hemorrhagic stroke, a frequent contributor to age-related cognitive impairment, and a key component in adverse responses to beta-amyloid (Aβ) ...

At the end of last month, a scientific journal pulled a research paper on Alzheimer’s disease. The retraction came from Neurobiology of Aging, which removed a 2011 paper claiming to show that a ...

Billions of dollars have been spent on Alzheimer's drugs that target Amyloid beta. While companies developing drugs to treat Alzheimer’s disease have spent decades and many billions of dollars ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...