Thyroid cancer cells undergo profound metabolic reprogramming to support rapid proliferation, survival under stress and metastatic spread. A hallmark of this reprogramming is the shift from ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

Pilatus Biosciences to Present Preclinical Data Highlighting Novel Metabolic Checkpoint Therapy PLT012 at EASL Congress 2026 ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Distinct cellular interactions in the TNBC tumor microenvironment in association with PD-L1 expression and pathologic complete response based on spatial analysis. This is an ASCO Meeting Abstract from ...

Poster presentation to showcase PLT012 targeting CD36 in metabolic dysfunction-associated steatohepatitis (MASH) Data demonstrate broad immune-metabolic reprogramming and reduction in key ...

This Research Topic is one volume within the series "The Future of Checkpoint Immunotherapy: New Roads Ahead". Please see the ...