The complement cascade, traditionally appreciated for its role in innate immunity, has emerged as a pivotal regulator of bone repair. Activation of complement components generates anaphylatoxins such ...

The complement system in teleost fish constitutes a cornerstone of innate defence, integrating classical, lectin and alternative activation routes to eliminate pathogens and shape inflammatory ...

The story of Q32 Bio, a company that develops therapeutics for inflammatory and autoimmune diseases, started two decades ago. That's when V. Michael Holers, MD, a University of Colorado School of ...