William asks the question many patients raise explicitly or implicitly: “Do these data really apply to me?” Dr. Wu answers ...

When adult data were extrapolated to pediatric populations in drug development programs, more than 61% of those extrapolations were linked to new product labeling, according to study results.

Extrapolating data from adult clinical trials to a pediatric population is a proven method to avoid unnecessary pediatric clinical trials. Representatives of the Pediatric Working Group of the IQ ...

Effect of mevalonate pathway inhibitors on outcomes of patients (pts) with HER2-positive early breast cancer (BC) in the ALTTO trial. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting ...

At the beginning of a new wave of an epidemic, extreme care should be used when extrapolating data to determine whether lockdowns are necessary, experts say. As the infectious virus causing the ...

A little more than a year after introducing the draft version, the US Food and Drug Administration (FDA) on Monday finalized guidance on how and when it may be appropriate to leverage existing ...

Mark Lebwohl, MD, details how he extrapolates clinical data in his decision-making when trying to treat patients with psoriasis. Ryan Haumschild, PharmD, MS, MBA: Given examples of some of the ...

The European Medicines Agency (EMA) released a reflection paper on Monday with the hope of helping drugmakers avoid unnecessary pediatric research by establishing a framework for extrapolating ...

WASHINGTON, May 19, 2020 -- As the infectious virus causing the COVID-19 disease began its devastating spread around the globe, an international team of scientists was alarmed by the lack of uniform ...