The R loop is a nucleic acid ménage à trois in which RNA inserts between the two DNA strands, hybridizing with one and forcing the other to bulge out. Identifying the genomic location of R loops is ...

This illustrative rendering of a 2.1 Mb region on chromosome 20 shows eight domains, six of which are demarcated by loops between convergent CTCF-binding sites located at the domain boundaries. The ...