Metabolic reprogramming in tumor immunology refers to alterations in nutrient uptake and intracellular pathways that enable both cancer cells and immune cells to survive, proliferate and exert ...

AbstractNon apoptotic cell death programs particularly ferroptosis and cuproptosis are transforming how we understand cancer ...

In response to ionising radiation, tumour cells undergo profound metabolic reprogramming that underpins their ability to survive and repair damage. Hallmarks of this process include a shift from ...

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

Tumor-associated macrophages (TAMs) are immune cells that tumors hijack to fuel their own growth and evade immune attack. A ...

However,instead of attacking cancer cells, they are typically co-opted to support tumor growth, metastasis, and therapeutic ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

相关研究成果以“Mitigating UV-B radiation effects on growth and grain yield of qingke via abscisic acid-induced pathways and ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...