Emulsions—mixtures of immiscible liquids such as oil and water—rely on surface‐active agents to stabilise dispersed droplets against coalescence and creaming. Proteins are among the most versatile ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Oxidative stress arises when the generation of reactive oxygen species overwhelms cellular antioxidant defences, leading to damage of biomolecules. Central to this process is lipid peroxidation, which ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they’re produced. Known as post-translational modifications, or PTMs, these can change how a ...

Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including ...

How might these modifications influence function? Would they increase or decrease protein function—and would there be consequences for T cell activation? To find out, the scientists harnessed a gene ...

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in ...

An AI model that reveals how protein modifications link genetic mutations to disease has been developed. Researchers at Baylor College of Medicine (TX, USA) have developed an AI model that reveals how ...

Scientists at the Baylor College of Medicine say they have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called ...

LA JOLLA, CA—Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, ...