MicroRNAs are short non-coding RNA molecules that regulate gene expression at the post-transcriptional level by guiding effector complexes to complementary sequences in target transcripts. In insects ...

Aging-related cognitive decline is an early symptom of Alzheimer's disease and other dementias, and on its own can have substantial consequences on an individual's ability to perform important ...

PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...

Researchers have found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared with that from normal controls. Specifically, methylation levels ...

Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...

A research team from the University of Eastern Finland and the University of Oxford says it has shown that small RNA molecules occurring naturally in cells, i.e., microRNAs, are also abundant in cell ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor ...

In the October15th issue of G&D, Dr. Fen-Biao Gao and colleagues at UCSF report that microRNA-9a (mir-9a) regulates neural development in the fruit fly, Drosophila. Using loss-of-function analysis, Dr ...

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the ...

Alfredo has a PhD in Astrophysics and a Master's in Quantum Fields and Fundamental Forces from Imperial College London. Alfredo has a PhD in Astrophysics and a Master's in Quantum Fields and ...

Only 1.1% of the nearly 3 billion molecules that make up our genome actually provide genetic instructions. When scientists first worked out what the sequence of letters in our genome was, they ...