Clinical Chemistry - Complement Cascade
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YouTubeMed Lab Technology 3D
Clinical Chemistry - Complement Cascade
In this video, we break down the Complement Cascade—a powerful immune system pathway involving over 30 proteins that work together to eliminate pathogens. You’ll learn how the Classical, Lectin, and Alternative pathways activate and converge at C3, leading to key outcomes like opsonization (C3b), inflammation (C3a, C4a, C5a), chemotaxis ...
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✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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